Antinociceptive properties of the essential oil of Ocimum gratissimum L. (Labiatae) in mice

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Antinociceptive properties of the essential oil of Ocimum gratissimum L. (Labiatae) in mice.

We have investigated the antinociceptive effects of the essential oil of Ocimum gratissimum L. (Labiatae) (EOOG) in two classical models of pain in male Swiss mice (25-35 g), the writhing test and the formalin test. At doses of 30, 100 and 300 mg/kg (po), EOOG produced a dose-dependent inhibition (from 58.3 4.4 to 40.7 6.3, 36.4 3.6 and 24.6 3.6, respectively; N = 8-10, P<0.05) of aceti...

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Antifungal activity, yield, and composition of Ocimum gratissimum essential oil.

Ocimum gratissimum L. or clove basil, belongs to the Lamiaceae family, has various desirable uses and applications. Beyond its aromatic, seasoning, and medicinal applications, this plant also has antimicrobial activity. This study was aimed at assessing the antifungal activity, yield, and composition of the essential oil (EO) of O. gratissimum. The species was cultivated in garden beds with dys...

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ژورنال

عنوان ژورنال: Brazilian Journal of Medical and Biological Research

سال: 2003

ISSN: 0100-879X

DOI: 10.1590/s0100-879x2003000400016